Welcome to the Desert Angels™. We are a Tucson, Arizona based non-profit organization of accredited investors who seek opportunities to invest in Southwest regional startup or early stage companies. The organization serves as a forum for its over 90 members, who invest individually from their personal funds. Since 2000, Desert Angel members have invested over $37 million in more than 85 presenting companies.

FDA Allows NuvOx Pharma’s IND to Initiate Phase Ib Clinical Trial in Stroke.

by Curtis Gunn on August 19th, 2016 at 5:06pm

Evan Unger, MD, President and CEO of NuvOx, announced that the FDA has allowed an investigational new drug application (IND) for NVX-208 (dodecafluoropentane emulsion) to be tested in a Phase Ib trial in stroke patients.

The trial will be performed at the University of Arkansas Medical System in Little Rock, Arkansas under the direction of Dr. William Culp, Jonathan Fitch Distinguished Chair in Stroke. Dr. Culp said, “We have studied NVX-208 in a number of pre-clinical stroke models and found that administration of NVX-208 decreases the brain damage from stroke by over 80%. The only approved drug to treat stroke is t-PA, which has a risk of bleeding and is approved for use only up to 3 hours following stroke. Administration of NVX-208 prior to t-PA extended the time window of efficacy to at least 9-hours. NVX-208 has great potential to allow many more stroke patients to be treated and to improve their outcomes. This trial will determine the recommended dose of NVX-208 in stroke patients so that it can be subsequently tested in a randomized study in stroke patients.”

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PR Product Recommendation: IrisPR Software

by Curtis Gunn on August 11th, 2016 at 5:05pm

We recently started using the new PR performance software tool IrisPR and we are loving it!

You can tell IrisPR is a tool created by PR professionals. With it, you can capture the names of your media contacts, gather the clips of the coverage you generate, and track the status of your PR campaigns and pitches! It’s as if your media database merged with your media monitoring service and all those spreadsheets of PR results that you’ve had to create yourself!

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Calimmune CEO Louis Breton Named to PharmaVOICE 100 for 2016

by Curtis Gunn on August 10th, 2016 at 3:34pm

Calimmune, Inc., a clinical-stage gene therapy company, is pleased to announce that its Chief Executive Officer, Louis Breton, has been selected by PharmaVOICE magazine as one of the top 100 most inspirational and extraordinary leaders in the life sciences industry for 2016.

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Playability Toys Nurture Smart Mobile Named Finalist for 2016 IDSA International Design Excellence Award

by Curtis Gunn on July 26th, 2016 at 4:50pm

Playability Toys, a leading maker of therapeutic toys and apps that enhance and improve the lives of children and their families, today announced that its Nurture Smart Mobile is an Industrial Designers Society of America’s (IDSA) 2016 International Design Excellence Award (IDEA) finalist in the Children’s Products category. The first and only clinical grade mobile of its kind, the Nurture Smart Mobile was judged by renowned design experts around the world among a field of more than 1,700 designs projects from 30-plus countries.

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HTG Molecular Diagnostics and Firalis Announce Agreement to Develop a Theranostic Tool to Predict Response to Anti-TNF-alpha Therapies for Rheumatoid Arthritis

by Curtis Gunn on July 19th, 2016 at 1:37pm

HTG Molecular Diagnostics, Inc. (Nasdaq:HTGM) (“HTG”), a provider of instruments and reagents for molecular profiling applications, and Firalis S.A. (“Firalis”), a provider of bioanalytical services and biomarker-based products to biopharma, to biotechnology companies, and to academia, announced an agreement to develop a next‑generation sequencing (NGS)-based theranostic tool to identify likely non-responders from responders to anti‑TNFα therapy for rheumatoid arthritis (RA).

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‘Huntsman’ tie-in a hit for Tucson game studio

by Curtis Gunn on July 11th, 2016 at 8:33pm

Tucson-based video game development studio Desert Owl Games continues to grow, with the launch of a “Huntsman” movie tie-in game, the 10-year anniversary of its biggest title and upcoming work with Sony.

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HTG Molecular Diagnostics Announces VERI/O Laboratory Service

by Curtis Gunn on June 27th, 2016 at 5:18pm

HTG Molecular Diagnostics, Inc. (Nasdaq:HTGM), a provider of instruments and reagents for molecular profiling applications, announced the introduction of its Tucson‑based VERI/O laboratory service, offering laboratory support for its biopharma clients in biomarker research and companion diagnostic development.

The VERI/O laboratory service formalizes and expands HTG’s traditional service offerings, including molecular profiling of retrospective cohorts to support development of targeted and immuno-oncology therapies, building custom research-use-only (RUO) assays to support early stage clinical programs, and developing companion diagnostic assays for use in Phase III registration trials.

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Man lives 555 days without a heart

by Curtis Gunn on June 21st, 2016 at 7:04pm

“It feels like a real heart”

It’s not the first time a patient has lived for a long time with an artificial heart, but Larkin became the first patient in Michigan to go home with the portable device.

The SynCardia temporary artificial heart in Larkin’s chest replaced his failing heart, including its chambers and four valves. Two tubes, exiting the left side of Stan’s body beneath the ribcage, connected the artificial heart to a 13-pound machine called the Freedom Driver.

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Top Companies: Best small companies to work for in Arizona

by Curtis Gunn on June 13th, 2016 at 5:04pm

Portfolio companies, Picmonic and Regenesis Biomedical, make Arizona best small company list.

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NuvOx Pharma Awarded STTR Grant from NCI for Ultrasound Contrast Agent to Diagnose Pancreatic Cancer

by Curtis Gunn on May 26th, 2016 at 7:20pm

Evan Unger, MD, President and CEO of NuvOx Pharma, a Tucson based biotechnology company, announced that the company has been awarded a grant from the National Cancer Institute to develop an ultrasound contrast agent to diagnose pancreatic cancer. The Phase I Small Business Technology Transfer (STTR) grant is a joint development project between NuvOx and Stanford University. The two principal investigators on the project are Drs. Unger and Juergen Willmann, MD, Chief of Body Imaging, Professor of Radiology, Stanford University, School of Medicine.

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